IMPORTED DRUGS AND MEDICINES FOR RARE AND/OR EXTREMELY RARE DISEASES

Pharmedic Pharmaceuticals seeks to advance prevention and treatment by simplifying access to special medicines for everyone.

frasco-med
Nitikabs
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Pentosan
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Bitartarato de Cisteamina
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Cloridrato de Trentina
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Foscarnet

RELIABILITY AND SCIENTIFIC INNOVATION FOR HEALTH

Pharmedic Pharmaceuticals has been present in the lives of patients with Rare Diseases worldwide for over 23 years, with the objective of providing safe and effective treatments in order to provide autonomy and quality of life for patients and their families.

Operating on four continents, in countries such as the United States of America, Colombia, Canada, India, Brazil and the United Arab Emirates, Pharmedic Pharmaceuticals seeks the most advanced therapeutic and medicinal methods for treating patients with rare and/or Extremely Rare Diseases.

The World Health Organization (WHO) defines a Rare Disease as one that affects up to 65 people per 100,000 individuals, or 1.3 people per 2,000 individuals.

Rare Diseases are characterized by a wide diversity of signs and symptoms that vary from person to person (even when affected by the same condition). They are often confused with common diseases, which makes early diagnosis difficult and causes great clinical and psychosocial suffering for those affected and their families.

Rare diseases are usually chronic, progressive, degenerative, and even disabling, affecting the quality of life of those affected and their families. 80% of known rare conditions are the result of genetic factors.

Today, data from the Ministry of Health estimates that about 13 million people in Brazil are affected by a rare health condition.

Rare diseases cannot be cured. However, proper treatment has great potential for reducing symptoms and complications and can inhibit the progression of the disease.

Pharmedic Pharmaceuticals is therefore active in the global search for therapeutic treatments that can provide greater autonomy and quality of life for those affected by rare and/or extremely rare diseases, ensuring a better quality of life.

LOOKING FOR A SPECIFIC MEDICATION?

Pharmedic Pharmaceuticals can find what you need anywhere in the world.

Nitibaks

Committed to quality of life, Pharmedic Pharmaceuticals was the first Brazilian company to provide access to effective and safe treatment for patients affected by Tyrosinemia.

PENTOSAN

Pentosan Polysulfate Sodium (PPS) is a drug used to treat interstitial cystitis and osteoarthritis.

Add-on: Interstitial Cystitis (IC), also known as Bladder Pain Syndrome (VPS), is a chronic disease of unknown etiology and progressive character, characterized by the presence of pain and accompanied by irritative urinary symptoms, inflammatory process that involves all or part of the bladder mucosa, and may reach the muscle wall.

The therapeutic approach includes behavioral, pharmacological, and even surgical interventions. Tablets and injectable solutions are recommended for the treatment of acute blood vessel obstructions, thrombophlebitis, subacute or chronic recurrent varicophlebitis. These methods are also suitable for the treatment of painful bladder syndrome, characterized by glomerulations or Hunner’s ulcers in adults with moderate to severe pain, urgency, and frequency of urination.

Topical use is recommended for mild to moderate muscle pain, bruising, and post-traumatic pain.

Cysteamine Bitartrate (Cystagon)

Cystagon is a drug that contains the active substance mercaptamine (also known as cysteamine). It is available in the form of 50 and 150 mg capsules.

Supplement: Cystagon is used for the treatment of Nephropathic (kidney) Cystinosis in children and adults. Cystinosis is a rare inherited disease in which excessive amounts of cystine, an amino acid naturally found in the body, accumulate inside cells, especially in the kidneys and eyes, damaging them. The progression of kidney failure can be slowed with early diagnosis and treatment.

Depending on the age of the patient and the severity of the disease, three clinical forms of cystinosis are distinguished: the infant nephropathy type, which is the most frequent (approximately 95% of cases) and most severe form of the disease, in which individuals usually develop clinical symptoms related to generalized proximal tubular dysfunction during the first year of life; the intermediate form (affecting about 5% of patients), usually diagnosed between the ages of 15 and 25, presenting milder manifestations of the childhood nephropathic form; and the adult non-nephropathic form (also known as ocular non-nephropathic cystinosis), characterized by photophobia resulting from the accumulation of cystine crystals in the cornea and rarely diagnosed before adulthood.

The drug improves the overall prognosis, delaying the progression to end-stage renal disease by about 6 to 10 years old and thus the need for kidney transplantation during childhood.

Trientine Hydrochloride

Trientine is a chelating agent capable of removing heavy metals from the blood, such as lead, mercury, and copper.

Supplement: Trientine Hydrochloride is recommended for the treatment of patients with Wilson’s disease (adults and pediatric patients 6 years of age and older) who are intolerant to penicillamine.

Wilson’s disease is an inherited condition that is characterized by the body’s inability to transport or eliminate copper normally as a secretion from the liver to the intestine.

This means that small amounts of copper from food and drink accumulate to excessive levels and can cause liver damage and nervous system problems.

The drug works by binding to copper in the body, which allows the metal to be eliminated in the urine and to be absorbed by the body in smaller amounts.

FOSCARNET

Antivirotic that acts against the Herpes group and Cytomegalovirus (CMV).

Complement: This new generation antivirotic, chemically called Trisodium Phosphonoformate, acts on different viral genera (herpes, shingles, CMV) with low toxicity to the infected host cells.

Like other similar antivirals (acyclovir or ganciclovir), Foscarnet acts as a specific inhibitory blocker of viral DNA-polymerase and prevents further DNA synthesis. Its mechanism of action inhibits the growth (by up to 90%) of DNA-polymerase viruses (herpes, CMV, hepatitis) and retroviruses with reverse transcriptase (HIV) without affecting cellular DNA. It has been demonstrated in vitro that the drug has activity against all human viruses belonging to the herpes group, hepatitis B, and some retroviruses, including the HIV genus.

Indicated for the treatment of viral infections by HIV, CMV and other genera, such as the Hepatitis B virus. Also suitable for patients with acquired immunodeficiency syndrome; cytomegalovirus retinitis in AIDS patients; and viral pneumonia, colitis, esophagitis, varicella zoster, herpes, and cytomegalovirus in immunocompromised patients.